Tuesday, January 30, 2007

Meeting with David

1. It’s better to see the high percentage of “birth surface curve”

2. Try to use “Spontaneous Term-Median Trajectory”  and move it down to see the effects of “birthing surface curve” and try to find the peak

3. I guess it may be useful to adjust the interval of our current division 

Posted by at 03:14:42 | Permalink | No Comments »

Monday, January 29, 2007

Meeting with David

1. I need to clear blow the preterm birth trajectory and get the number of “preterm/term/postterm” CRH again

2. Calculate the new “odds ratio” to see the change

3. Keep filtering by choosing “AFP” to get “CRH”

4. Keep calculating the new “odds ratio” to see the change 

Posted by at 06:43:07 | Permalink | No Comments »

Monday, January 22, 2007

Meeting with David

1. merge 27-31 and 31-34 together. Then the new interval is: 27-34; 34-37; 37-39; 39-40;40-42; >42; draw a horizontal line at the beginning of “birthing surface”

2. extend  each patient’s trajectory to cross with the “birthing surface”

3. filter data can be based on “minimum preterm trajectory”.

4. need to write a draft paper for “median trajectory” (last year’s work)<– before 1 Feb., 2007.

Posted by at 06:25:19 | Permalink | No Comments »

Wednesday, January 17, 2007

Meeting with David and Peter

1. Should re-work on “smooth birthing surface” building.

2. Other approach is correct and need further working

3. it is possible to only plot “smoking” people to see the change of “birthing surface”; and the other risk factors

4. future approach is to draw a possible trajectory range to predict

5. Using weighted points to determine which point is certain and which is not to better “curve fitting” 

 

Posted by at 03:23:42 | Permalink | No Comments »

Meeting with Hongxin and Guillermo

1. Hongxin recommends “Simon Warfield”, who develop software to seperate white/grey matter in 3D. Should contact Hongxin for his coming in March.

2. Clear Guillermo’s requirement:

1. geometry of brain

2. developping permeability value function (k=f(x,y))

Posted by at 01:07:46 | Permalink | No Comments »

Monday, January 15, 2007

Task on 15 Jan., 2007

1. Finished calculating new “median trajectory” for “spontaneous term birth” by using uniform axis-X

2. Modify plotting by using “uniform axis-X” and “uniform axis-Y”.

Furture work: Needs to compare “median trajectory” with each patient to filter some patients out 

Posted by at 06:38:23 | Permalink | No Comments »

Trend between preterm, term and post-term

CRH, Prog, Cortisol, hCG, AFP and ALP has the trend: preterm is always higher than term. Post-term is the minimum.
Posted by at 01:21:49 | Permalink | No Comments »

Friday, January 12, 2007

Hydrocephalus

1. Finish loading image in matlab

Problems:

1. need to learn image processing toolbox (imread…..)

2. may think load the whole MRI(.hdr format) in matlab

3. how to calculate the “permeability” value (What+How)

Posted by at 05:27:01 | Permalink | No Comments »

Wednesday, January 10, 2007

Building Birthing Surface

1. Finsihed building birthing surface by seperating patients in individual week. It’s not smooth enough, which will make the percentage calculation quite difficult.

2. Try to build smooth birthing surface by choosing: (1) minimum preterm birth patient (2)minimum term patient (3) minimum post-term patient (4) maximum post-term patient

It also has some line out of “birthing surface”, so this approach is not good.

3. Now, try to draw a horizonal line which has the minimum value of Y for all the patients to make sure it can cross with all the patients 

Posted by at 03:52:38 | Permalink | No Comments »

Wednesday, January 3, 2007

Possible Approach (Continue)

Once we build birthing surface for a specific parameter (i.e. CRH), we load a patient can get a possible risk rate. Then, we choose a different parameter, by choosing above the “Mean Trajectory” patients to filter more patients out to improve the risk rate.

Continue doing this for the other parameters (i.e. either above the “Mean Trajectory” or below the “Mean Trajectory”).

 

Posted by at 12:02:29 | Permalink | No Comments »